Which process describes the release of oxygen from haemoglobin to tissues?

Which process describes the release of oxygen from haemoglobin to tissues?

• A. Haemoglobin
• B. Bohr shift
• C. A-VO2 Difference
• D. Oxyhaemoglobin Dissociation

Answer: (D)

Oxygen release from haemoglobin to tissues is described by the dissociation of oxyhaemoglobin. In the lungs, haemoglobin binds oxygen to form oxyhaemoglobin. As blood reaches tissues, the local environment becomes less favorable for keeping onto oxygen (lower pO2, higher CO2 leading to lower pH, and often higher temperature). These changes reduce haemoglobin’s affinity for oxygen, causing the bound oxygen to detach and be delivered to tissues. This unloading process is what is meant by oxyhaemoglobin dissociation. The Bohr effect explains why these conditions promote release by lowering affinity, but the actual process term is dissociation. A-VO2 difference is a measurement of how much oxygen has been extracted, not the process itself, and haemoglobin refers to the protein, not the act of releasing oxygen.

Oxygen release from haemoglobin to tissues is described by the dissociation of oxyhaemoglobin. In the lungs, haemoglobin binds oxygen to form oxyhaemoglobin. As blood reaches tissues, the local environment becomes less favorable for keeping onto oxygen (lower pO2, higher CO2 leading to lower pH, and often higher temperature). These changes reduce haemoglobin’s affinity for oxygen, causing the bound oxygen to detach and be delivered to tissues. This unloading process is what is meant by oxyhaemoglobin dissociation. The Bohr effect explains why these conditions promote release by lowering affinity, but the actual process term is dissociation. A-VO2 difference is a measurement of how much oxygen has been extracted, not the process itself, and haemoglobin refers to the protein, not the act of releasing oxygen.